Meningitis Pathology Study Guide

CENTRAL NERVOUS SYSTEM PATHOLOGY
Central nervous system infections.a. Progressive Multifocal Leukoencephalopathy due to JC-virus infection, showing viral inclusion (arrow) and loss of myelin (H&E stain) b–c. Cryptococcal meningitis, showing Cryptococcus neoformans with a polysaccharide capsule (H&E stain)(b) and multiple narrow-necked budding yeast (Grocott Methanamine Silver stain) (c) d–f. Streptococcal meningitis, showing the macroscopic image of the brain with edema and purulent exudate (d), the subarachnoid space expanded by neutrophils and fibrin (H&E stain) (e) and Gram positive diplococci (arrow) (Brown-Hopps tissue Gram stain) (f).An autopsy study describing causes of death and comparing clinico-pathological findings among hospitalized patients in Kampala, Uganda. Cox JA, Lukande RL, Nelson AM, Mayanja-Kizza H, Colebunders R, Van Marck E, Manabe YC - PloS one (2012). Not Altered. CC.

Meningitis Meningitis is the technical term for inflammation of the leptomeninges. The leptomeninges are made of three layers: Dura mater Arachnoid Pia mater The meninges are located between the brain and the skull. Leptomeninges is the collective word for pia…

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