(A, B) Smaller gland lobes are seen in Fgf10 +/- adult submandibular glands (arrows) (scale bar=3mm). (C) Male and female Fgf10 +/- adult salivary glands show a significant decrease in salivary gland weight compared to WT littermates. (D-G) Male glands; no histological differences are noted between WT and Fgf10 +/- SMGs (D, E) SLGs (F, G), and GCTs (inset images D, E). D-G scale bar=200I1/4m, inset scale bar=50I1/4M. Salivary Gland Dysplasia in Fgf10 Heterozygous Mice: A New Mouse Model of Xerostomia: Current Medicinal Chemistry. Not altered. CC.
Xerostomia is dry mouth due to decreased saliva production. This can be due to medication side effects, radiation side effects, or inflammation. Xerostomia presents as dry mouth. Complications of xerostomia include oral candidiasis and dental cavities.
Xerostomia is classically associated with Sjögren’s syndrome.
