(A) Neonate with trisomy 18 and overlapping of the fingers associated with fingernail hypoplasia. (B) Kidneys from the same patient with nonobstructive renal dysplasia. (C) H&E-stained renal section with 2× lens, original magnification. Observe a small island of cartilage and disorganized renal parenchyma. (D) Another patient with trisomy 18 and horseshoe kidney. Congenital Anomalies of the Kidney and the Urinary Tract (CAKUT): Rodriguez MM - Fetal and pediatric pathology (2014). Not altered. CC.