Can Autoimmune Reactions Be Triggered By Infections?

Can Autoimmune Reactions Be Triggered By Infections
Muscle biopsy of right tibialis anterior (haematoxylin and eosin stain) showing changes consistent with multifocal myonecrosis, of marked interstitial inflammation mainly by CD4 lymphocyte with occasional fibre necrosis associated with CD4 inflammation.Recurrent myositis triggered by infections: a case report. Wong SH, Lecky BR, Hart IJ, Crooks D, Solomon T - Journal of medical case reports (2008). Not Altered. CC.

Yes, autoimmune reactions may be triggered by infections.

Such as the following:

  • Systemic Lupus Erythematosus – CMV, EBV, T. gondii
  • Antiphospholipid Syndrome – EBV, C. tetani, CMV
  • Type 1 diabetes – CMV, Saccharomyces cerevisiae
  • Rheumatoid arthritis – E.coli, K. pneumoniae, P. mirabilis, EBV, endogenous retrovirus
  • Multiple Sclerosis – EBV, Actinobacter sp., P. aeruginosa
  • Sjogren’s syndrome – coxsackie virus, EBV