What are Tumors of Bone or Cartilage of Unknown Origin?

Tumors of Bone or Cartilage of Unknown Origin
Pathological features of the mesenchymal chondrosarcoma from the thigh. (A) Macroscopic image of the tumor from the right thigh. (B) Areas with small round cells. (C and D) Biphasic growth pattern showing chondroid areas with transition to small round cells. (E) Positive immunohistochemical reaction of CD99.Chromosome aberrations and HEY1-NCOA2 fusion gene in a mesenchymal chondrosarcoma. Panagopoulos I, Gorunova L, Bjerkehagen B, Boye K, Heim S - Oncology reports (2014). Not Altered. CC.

Tumors of bone or cartilage of unknown origin are those tumors that originate elsewhere in the body with their location unknown but finally invade bone.

Examples of bone or cartilage of unknown origin include: 

  • Aneurysmal bone cyst
  • Ewing sarcoma family tumors
  • Giant cell tumor