Potter’s syndrome aka oligohydramios sequence occurs if the volume of amniotic fluid is less than normal for the corresponding period of gestation. The kidneys do not produce enough urine. The fetal urine is critical to the proper development of the lungs by aiding in the expansion of the airways by means of hydrodynamic pressure and by also supplying proline which is a critical amino acid for lung development. Without fetal urine, the alveoli remain underdeveloped at the time of birth, and the infant may not be able to breathe air properly. This may lead to respiratory distress shortly after birth due to pulmonary hypoplasia.