What is Acute Endometritis?

Acute Endometritis
Hematoxyline & Eosine stained tissue sections of normal endometrium; [a (10X), 1: columnar epithelial cells of endometrial lining, 2: endometrial glands], normal ectocervix [b (10X) 3: stratified squamous epithelial cells of ectocervix], and patients with chronic endometritis [c & d (20X & 40X), 4 & 5: Endometrial curettings showed mainly acute inflammatory exudate consisting of polymorphs and endometrial glands infiltrated by lymphocytes], chronic non-specific cervicitis [e & f (40X & 10X), 6 & 7: focal squamous metaplasia], chronic cervicitis [g & h, (10X & 40X), 8 & 9: endocervical curettings with fragmented endocervical tissue lined by endocervical lining epithelium of columnar cells] chronic salpingitis [i, (10X), 10: tissue sections from fallopian tube showed flattened tubal lining epithelium with loss of plica and some sections showed plical adhesions], chronic salpingo-oopheritis [j (40X), 11: fallopian tubes showed inflammatory infiltrate comprising plasma cells, lymphocytes and polymorphs}, acute on chronic cervicitis] [k (10X), 12 & 13: cervix showed keratinised lymphoplastic squamous epithelial lining and stroma with mild chronic inflammation, l (40X), 14: infammed stroma]. Characterization of low molecular weight antimicrobial peptide from human female reproductive tract. Sharma S, Sethi S, Prasad R, Samanta P, Rajwanshi A, Malhotra S, Sharma M - The Indian journal of medical research (2011). Not Altered. CC.

Acute endometritis is an inflammation or irritation of the lining of the uterus which is usually from an infection that passes through the cervix.

What is the Pathology of Acute Endometritis?

The pathology of acute endometritis is:

-Etiology: The cause of acute endometritis is infection due to chlamydia, gonorrhea, tuberculosis, more often after miscarriage or childbirth.

-Genes involved: NPSR1, ARID1A gene.

-Pathogenesis: The sequence of events that lead to acute endometritis is unknown.

-Morphology: The morphology associated with acute endometritis shows abdominal symptoms.

-Histology: The histology associated with acute endometritis shows neutrophils infiltrating and destroying endometrial epithelium.

How does Acute Endometritis Present?

Patients with acute endometritis typically females who are close to menopause. The symptoms, features, and clinical findings associated with acute endometritis include abnormal vaginal bleeding, swelling of the abdomen, bowel movement discomfort, and pelvic pain.

How is Acute Endometritis Diagnosed?

Acute endometritis is diagnosed by endometrial biopsy, bacterial cultures tests, laparoscopic procedures, blood tests for WBCs and RBCs. 

How is Acute Endometritis Treated?

Acute endometritis is treated by antibiotics.

What is the Prognosis of Acute Endometritis?

The prognosis of acute endometritis is good. Endometritis usually goes away with antibiotics without any further problems. However, problems with reproduction and severe infections can occur if the condition isn’t treated. These can lead to infertility.