What are Immature Teratomas?

Immature Teratomas
Immature Teratoma during ovarian stimulation. A: Macroscopic aspect: large irregular cyst with prominent solid component. The cystic areas are filled with fatty sebaceous material. No extra cystic vegetations. B: Pathological findings: Immature teratoma with nerve tissue of the embryonic type composed of glial tissue and neuro-ectodermal rosettes of 'primitive neural-tube' type (arrows). Inset: Pluritissued mature teratoma sector with cartilaginous tissue. Diagnosis and management of an immature teratoma during ovarian stimulation: a case report. Douay-Hauser N, Koskas M, Walker F, Luton D, Yazbeck C - Journal of medical case reports (2011). Not Altered. CC.

Immature teratomas are composed of tissues derived from the three germ layers and demonstrate clinically malignant behavior and are distinguished by the presence of immature or embryonic tissues.

What is the Pathology of Immature Teratomas?

The pathology of immature teratomas is:

-Etiology: The cause of immature teratomas is complications in differentiation.

-Genes involved: None.

-Pathogenesis: The sequence of events that lead to immature teratomas shows different tissues.

-Morphology: The morphology associated with immature teratomas shows cysts with serous or mucinous fluid.

-Histology: The histology associated with immature teratomas shows neurotubules or rosettes with different types of tissues.

How does Immature Teratomas Present?

Patients with immature teratomas typically in females at any age but mostly in first two decades of life. The symptoms, features, and clinical findings associated with immature teratomas include: Painful abdominal mass, bleeding.

How is Immature Teratomas Diagnosed?

Immature teratomas is diagnosed by blood test to estimate levels of AFP, CA-125, CA 19-9, and CEA, MRI, CT scan, ultrsonography.

How is Immature Teratomas Treated?

Immature teratomas is treated by surgery and chemotherapy.

What is the Prognosis of Immature Teratomas?

The prognosis of immature teratomas is good.