Mesotheliomas are a type of cancer that occurs in the thin layer of tissue that covers the majority of your internal organs mesothelium. Mesothelioma is an aggressive and deadly form of cancer.

What is the Pathology of Mesotheliomas?

The pathology of mesotheliomas is:

-Etiology: The cause of mesotheliomas is asbestos exposure.

-Genes involved: BAP1.

-Pathogenesis: The sequence of events that lead to mesotheliomas shows an aggressive tumor arising primarily from the pleural or peritoneal cavities. It develops by asbestos exposure after a long latency, which is characterized by insidious growth and clinical presentation at an advanced stage of disease.

-Histology: The histology associated with mesotheliomas shows epithelioid type, sarcomatoid type, biphasic type, desmoplastic type, among others.

How does Mesotheliomas Present?

Patients with mesotheliomas typically are all genders and mostly have disease at 69 years age. The symptoms, features, and clinical findings associated with mesotheliomas include: pain in the side of the chest or lower back, shortness of breath, cough, trouble swallowing feeling like food gets stuck, hoarseness, swelling of the face and arms.

How is Mesotheliomas Diagnosed?

Mesotheliomas is diagnosed by chest X-ray and a computerized tomography CT scan.

How is Mesotheliomas Treated?

Mesotheliomas is treated by surgery, chemotherapy, and immunotherapy.

What is the Prognosis of Mesotheliomas?

The prognosis of mesotheliomas is poor. The mesothelioma survival rates are typically 4–18 months after diagnosis, but there have been patients diagnosed with mesothelioma who have lived longer than 10 years. The current five-year survival rate for the disease is just 10 percent.