What is Ectopic Pregnancy?

Ectopic Pregnancy
(a) Laparoscopic view of the left Fallopian tube, containing the ectopic pregnancy (arrow). (b) Laparoscopic view of the right Fallopian tube, presenting a congestive dilatation mimicking an ectopic pregnancy (arrow). (c) Histological section of the left Fallopian tube which is distended and contains many chorionic villi (upper left part of the image), confirming extrauterine tubal pregnancy (hematoxylin and eosin stain; original magnification 25x). (d) Histological section of the right Fallopian tube which is distended by an oedematous mucosa with congestive blood vessels, with no chorionic villi (hematoxylin and eosin stain; original magnification 25x). Laparoscopic excision of coexisting left tubal and right pseudotubal pregnancy after conservative management of previous ectopic pregnancy with methotrexate: an unusual clinical entity. Xiromeritis P, Margioula-Siarkou C, Miliaras D, Kalogiannidis I - Case reports in surgery (2015). Not Altered. CC.

Ectopic pregnancy is the extrauterine implantation of a fertilized egg.

What is the Pathology of Ectopic Pregnancy?

The pathology of ectopic pregnancy is:

-Etiology: The cause of ectopic pregnancy is a pelvic inflammatory disease

-Genes involved: None.

-Pathogenesis: The sequence of events that lead to ectopic pregnancy includes four mechanisms including anatomic obstruction preventing passage of the zygote, abnormal conceptus, tubal motility abnormalities, zygote transperitoneal migration.

-Morphology: The morphology associated with ectopic pregnancy shows fallopian tubes which are a pair of hollow tubes attached one on each side of the uterus through which the egg travels from the ovary to the uterus. 

-Histology: The histology associated with ectopic pregnancy shows the presence of extrauterine chorionic villi or extravillous trophoblast

How does Ectopic Pregnancy Present?

Patients with ectopic pregnancy typically affect females present at the age range of 15-45 years. The symptoms, features, and clinical findings associated with ectopic pregnancy include vaginal bleeding or abdominal pain.

How is Ectopic Pregnancy Diagnosed?

Ectopic pregnancy is diagnosed using visualization of an extrauterine gestational sac by transvaginal ultrasound (TVUS) or histologic confirmation.

How is Ectopic Pregnancy Treated?

Ectopic pregnancy is treated by surgical management (typically salpingectomy or salpingotomy) for hemodynamically unstable patients and methotrexate.

What is the Prognosis of Ectopic Pregnancy?

The prognosis of ectopic pregnancy is poor if not treated in time.