Placental site trophoblastic tumor is a form of the gestational trophoblastic disease, which is thought to arise from the intermediate trophoblast.

What is the Pathology of Placental Site Trophoblastic Tumor?

The pathology of placental site trophoblastic tumor is:

-Etiology: The cause of placental site trophoblastic tumor is choriocarcinoma.

-Genes involved: None.

-Pathogenesis: The sequence of events that lead to placental site trophoblastic tumor shows a tumor neoplastic transformation of intermediate trophoblastic cells that normally play a critical role in implantation.

-Morphology: The morphology associated with placental site trophoblastic tumor shows trophoblast cells.

-Histology: The histology associated with placental site trophoblastic tumor shows proliferating intermediate trophoblast with scarce cytotrophoblasts and syncytiotrophoblastic elements.

How does Placental Site Trophoblastic Tumor Present?

Patients with placental site trophoblastic tumor typically affect females present at the age range of childbearing. The symptoms, features, and clinical findings associated with placental site trophoblastic tumor include vaginal bleeding and amenorrhoea, low beta HCG levels. 

How is Placental Site Trophoblastic Tumor Diagnosed?

Placental site trophoblastic tumor is diagnosed using blood tests and ultrasound. 

How is Placental Site Trophoblastic Tumor Treated?

Placental site trophoblastic tumor is treated with hysterectomy.

What is the Prognosis of Placental Site Trophoblastic Tumor?

The prognosis of placental site trophoblastic tumor is poor.