Hamartomas of the lung are noncancerous tumors that are formed after an abnormal mixture of normal cells and normal tissues e.g. cartilages, fat, muscle, or epithelium in the lungs.
What is the Pathology of Hamartomas of the Lung?
The pathology of hamartomas is:
-Etiology: The cause of hamartoma of the lung is not well defined but can be seen to be predisposed by other conditions.
-Genes involved: BMPR1A, SMAD4, PTEN, STK11.
-Pathogenesis: The sequence of events that lead to hamartoma of the lung is continuous abnormal replication of the normal tissue cells of the lungs.
-Histology: The histology associated with hamartoma of the lung shows a mixture of mature tissue of the mesenchyme which includes cartilages, adipose tissue, and smooth muscle tissues.
How does Hamartoma of the Lung Present?
Patients with hamartoma of the lung typically is higher in males than females with a mean age range of 20-77 years. The symptoms, features, and clinical findings associated with hamartoma of the lung include dyspnea, wheezing, coughing, productive cough, fever, and hemoptysis.
How is Hamartoma of the Lung Diagnosed?
The hamartoma of the lung is diagnosed radiologically using MR, CT-scan, chest x-ray.
How is Hamartomas of the Lung Treated?
The hamartoma of the lung is treated mostly by a surgical procedure that is known as the sleeve resection lobectomy.
What is the Prognosis of Hamartoma of the Lung?
The prognosis of hamartoma of the lung is good. This is because this tumor is slow-growing and even when it is fully grown it occurs in small sizes making the survival rate after resection good