What is Von Willebrand Disease?

Von Willebrand Disease
Von Willebrand Disease. Cytologically bland lobular capillary proliferation with variable cellularity. The overlying epithelium is flattened and forms a peripheral collarette (×4, H&E).Hematological evaluation of acquired von Willebrand syndrome before oral surgery: Management of an unusual case. Bombeccari GP, Guzzi G, Bucciarelli P, Pallotti F, Spadari F - Asian journal of transfusion science (2012). Not Altered. CC.

Von Willebrand disease is a blood disorder in which the blood does not clot properly.

What is the Pathology of the Von Willebrand Disease?

The pathology of von Willebrand disease is:

-Etiology: The cause of von Willebrand disease is an inherited abnormal gene that controls the von Willebrand factor.

-Genes involved: vWF gene.

-Pathogenesis: The sequence of events that lead to von Willebrand disease is a hereditary defect in vWF.

How does Von Willebrand Disease Present?

Patients with von Willebrand disease typically are either male or female present at the age range of infants. The symptoms, features, and clinical findings associated with von Willebrand disease include excessive bleeding.

How is Von Willebrand Disease Diagnosed?

Von Willebrand disease is diagnosed with a medical history, physical exam, platelet testing, and genetic testing.

How is Von Willebrand Disease Treated?

Von Willebrand disease is treated with desmopressin.

What is the Prognosis of the Von Willebrand Disease?

The prognosis of von Willebrand disease is fair.