The Three Features of APL The three features of APL are (A) accumulation of abnormal promyelocytes, (B) fibrinogenopenia and disseminated intravascular coagulation, and (C) the chromosomal translocation t(15;17)(q22;q21), the resultant fusion transcripts, and variants. Retinoic acid and arsenic for treating acute promyelocytic leukemia. Zhou GB, Zhao WL, Wang ZY, Chen SJ, Chen Z - PLoS medicine (2005). Not Altered. CC.