Hemophilia A is an X-linked, recessive bleeding disorder.

What is the Pathology of Hemophilia A?

The pathology of hemophilia A is:

-Etiology: The cause of hemophilia A is an inherited or acquired genetic mutation that results in deficiency or dysfunction of factor VIII.

-Genes involved: X linked FVIII.

-Pathogenesis: The sequence of events that lead to hemophilia A is abnormal or absence of factor VIII clotting factor.

How does Hemophilia A Present?

Patients with hemophilia A typically are males that present with excessive bleeding at a young age. Other symptoms, features, and clinical findings associated with hemophilia A include easy bruising, hemarthrosis, and epistasis.

How is Hemophilia A Diagnosed?

Hemophilia A is diagnosed with medical history, and clotting factor tests.

How is Hemophilia A Treated?

Hemophilia A is treated with factor replacement as needed.

What is the Prognosis of Hemophilia A?

The prognosis of hemophilia A is fair.