Acute drug-induced Interstitial nephritis is a disease of the interstitium that occurs due to the hypersensitivity reaction towards a certain drug.

What is the Pathology of Acute Drug-Induced Interstitial Nephritis?

The pathology of acute drug-induced interstitial nephritis is:

-Etiology: The cause of acute drug-induced interstitial nephritis is hypersensitivity to drugs, 

-Genes involved: Unknown. 

-Pathogenesis: The sequence of events that lead to acute drug-induced interstitial nephritis toxicity from the ingested drugs causes a hypersensitive reaction to the nephrons of the kidneys leading to nephritis.

-Morphology: Unknown. 

-Histology: Interstitial inflammatory infiltrate. 

How does Acute Drug-Induced Interstitial Nephritis Present? 

Patients with acute drug-induced interstitial nephritis typically present at the age range of 40-80 years. The symptoms, features, and clinical findings associated with acute drug-induced interstitial nephritis include rash fever, eosinophilia after 7 days of consumption of the medicine.

How is Acute Drug-Induced Interstitial Nephritis Diagnosed? 

Acute drug-induced interstitial nephritis is diagnosed kidney biopsy, physical examination and history taking.

How is Acute Drug-Induced Interstitial Nephritis Treated? 

Acute drug-induced interstitial nephritis is treated by mainly withdrawing the suspected medication, corticosteroids.

What is the Prognosis of Acute Drug-Induced Interstitial Nephritis?

The prognosis of acute drug-induced interstitial nephritis is fair if the medication is withdrawn.