Bile cast Nephropathy also known as cholemic nephropathy, is an acute kidney injury that may be caused by increased bilirubin or bile acids levels.

What is the Pathology of Bile Cast Nephropathy?

The pathology of bile cast nephropathy is:

-Etiology: The cause of bile cast nephropathy is not well understood but some factors are obstruction of the kidney tubules, toxicity from bile acids, and systemic hypoperfusion.

-Genes involved: Unknown. 

-Pathogenesis: The sequence of events that lead to bile cast nephropathy is when there are increased amounts of bilirubin in the kidney that cause damage to the tubules leading to nephropathy.

-Morphology: The morphology associated with bile cast nephropathy shows bilirubin casts deposition in the distal, nephron, 

-Histology: The histology associated with bile cast nephropathy shows yellow cortex, bilirubin casts deposition.

How does Bile Cast Nephropathy Present? 

Patients with bile cast nephropathy typically are male present at the age range of 30-80 years. The symptoms, features, and clinical findings associated with bile cast nephropathy include acute jaundice, renal insufficiency.

How is Bile Cast Nephropathy Diagnosed? 

Bile cast nephropathy is diagnosed by physical and history taking, kidney biopsy, blood tests, bilirubin levels.

Bile cast nephropathy is a treatment for reduction in the levels of bilirubin and bile salts, renal replacement therapy.

How is Bile Cast Nephropathy Treated? 

Bile cast nephropathy is treated symptomatically. 

What is the Prognosis of Bile Cast Nephropathy?

The prognosis of bile cast nephropathy is fair if diagnosed early and appropriate management adhered to.