What is Bile Duct Obstruction?

Bile Duct Obstruction
A: Three-dimensional computed tomography reconstruction found an extrahepatic bile duct obstruction (arrow); B: MRI coronal image confirmed entire extrahepatic bile duct obstruction (arrows); C: Tumor (arrow) seen at the incision of the common bile duct; D: Tumor (arrow) seen in the common bile duct by intraoperative choledochoscopy; E: Uppercut end of the hepatic common duct (arrows); F: The cut end of the pancreas (arrow), and the portal vein; G: Child anastomosis (arrows); H: Resected specimen following pancreatoduodenectomy; I: Papillary adenocarcinoma of the extrahepatic bile duct, including the hepatic common duct, common bile duct, and Vater ampulla. Hematoxylin and eosin staining. Objective magnification, × 40. Therapeutic experience of 289 elderly patients with biliary diseases: World Journal of Gastroenterology. Not altered. CC.

Bile duct obstruction is a condition when one of the ducts that carry bile from the liver to the intestine via the gallbladder becomes blocked.

What is the Pathology of Bile Duct Obstruction?

The pathology of bile duct obstruction is:

-Etiology: The cause of bile duct obstruction is gallstones

-Genes involved: None.

-Pathogenesis: The sequence of events that lead to bile duct obstruction might include pancreatitis or an injury to the abdomen.

-Histology: The histology associated with bile duct obstruction shows centrilobular canalicular cholestasis, followed shortly by portal tract edema, ductular reaction, and mild chronic inflammation.

How does Bile Duct Obstruction Present?

Patients with bile duct obstruction typically affect females present at the age range of 30-40. The symptoms, features, and clinical findings associated with bile duct obstruction include jaundice, nausea, vomiting, abdominal pain, fever. Without treatment, bile duct obstruction may progress to fibrosis and cirrhosis with duct loss.

How is Bile Duct Obstruction Diagnosed?

Bile duct obstruction is diagnosed typically by clinical presentation and radiologic findings.

How is Bile Duct Obstruction Treated?

Bile duct obstruction is treated with cholecystectomy and an ERCP.

What is the Prognosis of Bile Duct Obstruction?

The prognosis of bile duct obstruction is poor causing life-threatening infections.

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Last updated on May 24, 2022