What is Squamous Cell Carcinoma of the Penis?

Squamous Cell Carcinoma of the Penis
: Histological findings showed triple cancer (magnification of background image: ×40, insert: ×400). (a) Hematoxylin-eosin (HE) staining of the small cell carcinoma of the bladder. (b) Immunohistochemical staining for CD56 demonstrated CD56-positive cells. (c) HE staining of the prostatic urethral tumor demonstrated papillary growth and malignancy. (d) HE staining of the penis showed cancer pearls and single-cell keratinocytes that are characteristic of squamous cell carcinoma.The probability of involvement of human papillomavirus in the carcinogenesis of bladder small cell carcinoma, prostatic ductal adenocarcinoma, and penile squamous cell carcinoma: a case report. Ogawa S, Yasui T, Taguchi K, Umemoto Y, Kojima Y, Kohri K - BMC research notes (2014). Not Altered. CC.

Squamous cell carcinoma of the penis is a lesion that usually begins on the glans or inner surface of the prepuce near the coronal sulcus.

What is the Pathology of Squamous Cell Carcinoma of the Penis?

The pathology of squamous cell carcinoma of the penis is: 

-Etiology: The cause of squamous cell carcinoma of the penis is malignant keratinocytes.

-Genes involved: Unknown. 

-Pathogenesis: The sequence of events that lead to squamous cell carcinoma of the penis involves growth of malignant keratinocytes.

-Morphology: The morphology associated with squamous cell carcinoma of the penis shows a squamous lesion. 

-Histology: The histology associated with squamous cell carcinoma of the penis shows dyskeratosis, epidermal acanthosis, parakeratosis, and epidermal atypia.

How does Squamous Cell Carcinoma of the Penis Present? 

Patients with squamous cell carcinoma of the penis typically have nodular lesions. The symptoms, features, and clinical findings associated with squamous cell carcinoma of the penis include visible skin lesions. 

How is Squamous Cell Carcinoma of the Penis Diagnosed? 

Squamous cell carcinoma of the penis is diagnosed by physical exam and biopsy.

How is Squamous Cell Carcinoma of the Penis Treated? 

Squamous cell carcinoma of the penis is treated through medical therapy, radiation therapy, and surgery, and laser therapy.

What is the Prognosis of Squamous Cell Carcinoma of the Penis?

The prognosis of squamous cell carcinoma of the penis is fair depending on staging and management.

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Last updated on May 24, 2022