Undifferentiated pleomorphic sarcoma is malignant mesenchymal tumors with pleomorphic cells that are high grade that does not meet the criteria of other classes of soft tissue tumors.

What is the Pathology of Undifferentiated Pleomorphic Sarcoma?

The pathology of undifferentiated pleomorphic sarcoma is:

-Etiology: The cause of undifferentiated pleomorphic sarcoma is unknown.

-Genes involved: None.

-Pathogenesis: The sequence of events that lead to undifferentiated pleomorphic sarcoma is poorly understood.

-Morphology: The morphology associated with undifferentiated pleomorphic sarcoma shows spindle, round/epithelioid, or pleomorphic, demonstrating marked cytologic atypia.

-Histology: The histology associated with undifferentiated pleomorphic sarcoma shows single or clustered spindled cells with nuclear pleomorphism.

How does Undifferentiated Pleomorphic Sarcoma Present?

Patients with undifferentiated pleomorphic sarcoma typically affect males present at the age range of 15-85 years. The symptoms, features, and clinical findings associated with undifferentiated pleomorphic sarcoma present as rapidly enlarging palpable mass but can be incidental findings at screening.

How is Undifferentiated Pleomorphic Sarcoma Diagnosed?

Undifferentiated pleomorphic sarcoma is diagnosed using a biopsy.

How is Undifferentiated Pleomorphic Sarcoma Treated?

Undifferentiated pleomorphic sarcoma is treated using surgical resection.

What is the Prognosis of Undifferentiated Pleomorphic Sarcoma?

The prognosis of undifferentiated pleomorphic sarcoma is poor with a 5-year overall survival rate of 50%.