What is Kaposi Sarcoma?

Kaposi Sarcoma HHV8 Stain aka LNA-1

Kaposi Sarcoma. Nodular Kaposi sarcoma.A. The dermis is expanded by a solid tumor nodule (H&E stain). B. Fascicles of relatively monomorphic spindled cells, with slit-like vascular channels containing erythrocytes (H&E stain). C. The nuclei of the tumor cells demonstrate immunoreactivity for HHV-8 (LNA-1 immunohistochemical stain). Histological variants of cutaneous Kaposi sarcoma. Grayson W, Pantanowitz L - Diagnostic pathology (2008). Not altered. CC.

Kaposi sarcoma is an indolent angio proliferative spindle cell tumor derived from endothelial and immune cells infected with human herpes virus type 8.

What is the Pathology of Kaposi Sarcoma?

The pathology of Kaposi sarcoma arises as a cancer of lymphatic endothelium and forms vascular channels that fill with blood cells.

How does Kaposi Sarcoma Present?

Kaposi sarcoma presents with cutaneous lesions especially on the lower extremities, head and neck, non pruritic palpable lesions, brown, red or pink colored lesions.

How is Kaposi Sarcoma Diagnosed?

Kaposi sarcoma is diagnosed by microscopic examination of tissue biopsy, and medical imaging.

How is Kaposi Sarcoma Treated?

Kaposi sarcoma is treated with radiation therapy, cryosurgery, chemotherapy, and antiretroviral beta-blocker.

What is the Prognosis of Kaposi Sarcoma?

The prognosis of Kaposi sarcoma is dependent on the extent of disease.

Last updated on May 23, 2022