What is an Odontogenic Fibroma?

Odontogenic Fibroma
Histopathological and immunohistochemical features of ossifying variant of odontogenic fibroma. a) odontogenic fibroma demonstrates cellular fibroblastic connective tissue with numerous islands and cords of odontogenic epithelium. Reactive bone formation involves the lesion (haematoxylin and eosin (HE staining, 40x original magnification). b) Abundant calcified structures and presence of surrounding conjunctive tissue. c) Islands and cords of odontogenic epithelium, fibroblastic connective tissue and bone formation (HE, 100x original magnification). d) Immunohistochemical staining positive for CK14 in islands and cords of odontogenic epithelium (streptavidin-biotin, 400x original magnification). Ossifying odontogenic fibroma: A rare case report. Amaral MB, Souto GR, Horta MC, Gomez RS, Mesquita RA - Journal of clinical and experimental dentistry (2014). Not ALtered. CC.

Odontogenic fibroma is an extremely rare benign tumor that accounts for 0.1% of all odontogenic tumors. It appears as an asymptomatic expansion of the cortical plate of the mandible or maxilla. 

What is the Pathology of Odontogenic Fibroma?

The pathology of odontogenic fibroma is:

-Etiology: The cause of odontogenic fibroma is unknown.

-Genes involved: None.

-Pathogenesis: The sequence of events that lead to odontogenic fibroma is  a proliferation of mature odontogenic mesenchyme.

-Histology: The histology associated with odontogenic fibroma shows cellular fibro collagenous tissue with scattered, small, inactive odontogenic epithelium in strands, cords, or nests.

How does Odontogenic Fibroma Present?

Patients with Odontogenic Fibroma typically affect females present in the age range of 20-40 years. The symptoms, features, and clinical findings associated with odontogenic fibroma include swelling and pain.

How is Odontogenic Fibroma Diagnosed?

Odontogenic fibroma is diagnosed depending on clinical, radiologic, and pathologic correlation.

How is Odontogenic Fibroma Treated?

Odontogenic fibroma is treated by excision, enucleation, and curettage

What is the Prognosis of Odontogenic Fibroma?

The prognosis of odontogenic fibroma depends on the type of odontogenic fibroma.