What is Neuropathy Associated with Systemic Autoimmune Diseases?

Neuropathy Associated with Systemic Autoimmune Diseases
Neuropathy Associated with Systemic Autoimmune Diseases. (A) Fundus photograph taken at initial examination of the right eye shows a chalky, white disc swelling. (B, C) Histopathology presentations of a right temporal arterial biopsy. (B) Diffuse thickening of the intima and fragmentation of the internal elastic lamina of the arterial wall (elastin stain, ×40). (C) Inflammatory cells within the arterial wall, especially in the media (H&E, ×40). (D) After 1 month of treatment, a pale optic disc was found in the right eye. Arteritic Anterior Ischemic Optic Neuropathy Associated with Giant Cell Arteritis in an Elderly Korean Man: Kang YS, Park SW, Lee HK, Choi YD, Heo H - Korean journal of ophthalmology: KJO (2016). Not altered. CC.

Neuropathy associated with systemic autoimmune diseases is a group of immune-mediated neuropathies that sporadically present in patients with systemic autoimmune ailments.

What is the Pathology of Neuropathy Associated with Systemic Autoimmune Diseases?

The pathology of neuropathy associated with systemic autoimmune diseases is: 

-Etiology: The cause of neuropathy associated with systemic autoimmune diseases is ill regulation of innate and adaptive immunity.

-Genes involved: NA.

-Pathogenesis: The sequence of events that lead to neuropathy associated with systemic autoimmune diseases results from an impairment of the nutrient supply of peripheral nerves by neuronal cell body and blood vessels causing malfunctioning.

-Morphology: NA.

-Histology: NA.

How does Neuropathy Associated with Systemic Autoimmune Diseases Present? 

Patients with neuropathy associated with systemic autoimmune diseases typically have no gender prevalence present at the age range of any age. The symptoms, features, and clinical findings associated with neuropathy associated with systemic autoimmune diseases include paresthesia, malaise, weight loss, fever, and night sweats.

How is Neuropathy Associated with Systemic Autoimmune Diseases Diagnosed? 

Neuropathy associated with systemic autoimmune diseases is diagnosed through clinical presentations. Cerebrospinal fluid (CSF) analysis, CBCs, biochemical profile, urine immune-electrophoresis may be helpful. Other studies such as spine MRI, electromyography (EMG) and peripheral nerve biopsy may be warranted.

How is Neuropathy Associated with Systemic Autoimmune Diseases Treated? 

Neuropathy associated with systemic autoimmune diseases is treated by managing the underlying condition.

What is the Prognosis of Neuropathy Associated with Systemic Autoimmune Diseases?

The prognosis of neuropathy associated with systemic autoimmune diseases is good, with proper management of the underlying condition.