WHAT IS PERIPHERAL NERVOUS SYSTEM PATHOLOGY?

PERIPHERAL NERVOUS SYSTEM PATHOLOGY
Peripheral Nervous System Pathology. (A) Paraffin-embedded transverse section of the sural nerve of patient 4 stained with hematxylin-eosin, showing perivascular infiltrate of mononuclear cells in the epineurium. (B) Paraffin-embedded longitudinal section of the radial nerve of patient 5, showing massive infiltrates of mononuclear cells in the epineurium. (C) Frozen tranverse section of the sural nerve of patient 7 stained with anti-CD45 antibody, showing a perivascular epineurial T-cell infiltrate. (D) Paraffin-embedded transverse section of the sural nerve of patient 8, stained with hematoxylin-eosin. Two middle-size vessels of the epineurium display the typical aspect of necrotizing vasculitis. Value of nerve biopsy in patients with latent malignant hemopathy and peripheral neuropathy: a case series: Duchesne M, Mathis S, Corcia P, Richard L, Ghorab K, Jaccard A, Magy L, Vallat JM - Medicine (2015). Not altered. CC.

Peripheral nervous system pathology is any disease or disorder that affects the peripheral nervous system. 

Examples of peripheral nerve pathology include:

  • Diseases of peripheral nerves
  • Inflammatory neuropathies
  • Infectious neuropathies
  • Hormonal neuropathies
  • Metabolic and nutritional neuropathies
  • Toxic neuropathies
  • Malignancy associated neuropathies
  • Neuropathies caused by physical forces
  • Inherited peripheral neuropathies
  • Diseases of the neuromuscular junction
  • Peripheral nerve sheath tumors