What is Hyperparathyroidism?

Hyperparathyroidism
Hyperparathyroidism. Histopathological findings of parathyroid adenoma in patients (control) with primary hyperparathyroidism without a hyperparathyroidism-induced hypercalcemic crisis (HIHC), (a) Adenoma: Microphotograph showing absence of microcystic pattern, intracytoplasmic vacuoles, and intraglandular fibrosis (H and E, ×100 magnification), (b) Adenoma with capsule: Microphotograph showing thin capsule of parathyroid adenoma. There is an absence of microcystic pattern, intracytoplasmic vacuoles, and intraglandular fibrosis (H and E, ×100 magnification). Primary hyperparathyroidism presenting as hypercalcemic crisis: Twenty-year experience: Singh DN, Gupta SK, Kumari N, Krishnani N, Chand G, Mishra A, Agarwal G, Verma AK, Mishra SK, Agarwal A - Indian journal of endocrinology and metabolism (2015 Jan-Feb). Not altered. CC.

Hyperparathyroidism is a disease caused by over secretion of parathyroid hormone (PTH). Inappropriately elevated parathyroid hormone level, may cause hypercalcemia. Hyperparathyroidism is classified as primary, secondary and tertiary. 

What is Primary Hyperparathyroidism? 

Primary hyperparathyroidism is a condition caused by over secretion of PTH.

What is Parathyroid Hyperplasia? 

Parathyroid hyperplasia is an increase of the number of cells in one or more parathyroid glands. Parathyroid hyperplasia may be diffuse or nodular.

What is a Parathyroid Adenoma? 

A parathyroid adenoma is the main cause of primary hyperparathyroidism, present in about 90% of the primary-form cases.

What is Parathyroid Carcinoma? 

A parathyroid carcinoma is a malignant parathyroid lesions.

What is Secondary Hyperparathyroidism? 

Secondary hyperparathyroidism is a condition in which parathyroid levels are high due to tissues not responding to parathyroid hormone or malignancies.

Conditions that cause secondary hyperparathyroidism include: 

  • Severe calcium deficiency
  • Severe vitamin D deficiency
  • Chronic kidney failure

What is Tertiary Hyperparathyroidism? 

Tertiary hyperparathyroidism is an excessive production of parathyroid hormone that does not respond to feedback controls.

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Last updated on May 23, 2022