What is Nodular Fasciitis?

Nodular Fasciitis
Nodular Fasciitis. Photomicrograph showed the features of nodular fasciitis with nodular proliferation of spindle to oval cells and giant cells admixed with collagenous stroma (H&E, ×200). Imaging findings for malignancy-mimicking nodular fasciitis of the breast and a review of previous imaging studies. Son YM, Nahm JH, Moon HJ, Kim MJ, Kim EK - Acta radiologica short reports (2013). Not Altered. CC.

Nodular fasciitis is a benign, soft tissue tumor.

What is the Pathology of Nodular Fasciitis? 

The pathology of nodular fasciitis is: 

-Etiology: The cause of nodular fasciitis is unknown. However, it is thought to be the local reaction to traumatic injuries. 

-Genes involved: USP-6 and MYH-9.

-Pathogenesis: The sequence of events that lead to nodular fasciitis involves the self-limiting growth of a clone of neoplastic cells that contain a fusion gene. 

-Histology: The histology associated with nodular fasciitis shows spindle-shaped myofibroblastic cells.

How does Nodular Fasciitis Present? 

Patients with nodular fasciitis typically affect both males and females present at an age range of 20-40 years. The symptoms, features, and clinical findings associated with nodular fasciitis show mild pain, discomfort, or soreness. 

How is Nodular Fasciitis Diagnosed? 

Nodular fasciitis is diagnosed through a sonogram, MRI, CT scan, and biopsy.

How is Nodular Fasciitis Treated? 

Nodular fasciitis is treated by simple excision.

What is the Prognosis of Nodular Fasciitis? 

The prognosis of nodular fasciitis is excellent.