Exocytosis. Exocytosis of MVEs releases exosomes containing transferrin receptor. (left) View of an MVE from a fixed reticulocyte sparsely labeled with AuTf. The apparent fusion of the MVE and the plasma membrane may represent incipient MVE exocytosis. Bar, 100 nm. (right) View of MVE exocytosis in a reticulocyte labeled with AuTf, quick frozen without prior fixation, and freeze substituted. Bar, 200 nm. Figure and legend adapted from Harding et al. (1983). Exosomes: looking back three decades and into the future. Harding CV, Heuser JE, Stahl PD - The Journal of cell biology (2013). Not Altered. CC.