Thyrotoxicosis is the clinical manifestation of excess thyroid hormone action at the tissue level due to inappropriately high circulating thyroid hormone concentrations.

What is the Pathology of Thyrotoxicosis? 

The pathology of thyrotoxicosis is mainly due to the release of preformed thyroid hormone into the circulation as inflammation destroys thyroid follicles.

How does Thyrotoxicosis Present? 

Thyrotoxicosis usually presents with heat intolerance associated with increased sweating, weight loss with a normal or increased appetite, palpitations, tremor, anxiety, proximal muscle weakness, alopecia and increased fatiguability. 

How is Thyrotoxicosis Diagnosed? 

Thyrotoxicosis is diagnosed by thyroid function tests including TSH, T3, and FT4.

How is Thyrotoxicosis Treated? 

Thyrotoxicosis is treated by symptomatic management. These may include beta-blockers and radioactive iodine.

What is the Prognosis of Thyrotoxicosis? 

The prognosis of thyrotoxicosis is good, but if thyrotoxicosis is not treated properly delirium, altered mental status, osteoporosis, muscle weakness, atrial fibrillation, may occur.