Sections of cartilaginous tissues from a female LEW.1F rat immunized with matrilin-1 [3]. An erosive inflammation is detected in the nasal septum (a) and in the laryngeal part of the respiratory tract (b) with an influx consisting mainly of neutrophils but also of lymphocytes, macrophages and eosinophils. Hematoxylin and erythrosine staining. Reproduced with the permission of the American Society for Clinical Investigation Inc. Cartilage-specific autoimmunity in animal models and clinical aspects in patients - focus on relapsing polychondritis. Hansson AS, Holmdahl R - Arthritis research (2002). Not Altered. CC.