What is a Melanoma of the Larynx?

Melanoma of the larynx
Melanoma of the larynx. Spindle and epithelioid malignant cells adjacent to intact and atrophic squamous epithelium that recovered the oral mucosa. Melanin was not observed (H&E, ×200). Metastases of Melanoma to Head and Neck Mucosa: A Report of Short Series: Santos RS, Andrade MF, Alves Fde A, Kowalski LP, Perez DE - Clinical and experimental otorhinolaryngology (2016). Not Altered. CC.

Melanoma of the larynx is is an extremely very erratic, aggressive neoplasm of melanocytic origin with very little known about it.

What is the Pathology of Melanoma of the Larynx?

The pathology of melanoma of the larynx is:

-Etiology: The cause of melanoma of the larynx is poorly unstated though tobacco use and formaldehyde exposure are suggested.

-Genes involved: BRAF mutation.

-Pathogenesis: The sequence of events that lead to melanoma of the larynx not yet known.

-Histology: The histology associated with melanoma of the larynx shows the tumor consisting of polygonal-epithelioid cells, spindle-shaped and elongated cells. Most cells establish dark-brown cytoplasmic also nuclear melanin. Noticeable abnormal mitoses and pleomorphism were noted. 

How does Melanoma of the Larynx Present? 

Patients with melanoma of the larynx typically have equal gender distribution, preset at age range of 20- 80 years. The symptoms, features, and clinical findings associated with melanoma of the larynx include sore throat, Hoarseness, and sporadic breathing difficulties. Dark color masses on the epiglottis.

How is Melanoma of the Larynx Diagnosed? 

Melanoma of the larynx is diagnosed through immunohistochemical and histopathologic examination. 

How is Melanoma of the Larynx Treated?

Melanoma of the larynx is treated through laryngeal lesions, a total surgical excision, and postoperative radiation therapy. 

What is the Prognosis of Melanoma of the Larynx?

The prognosis of melanoma of the larynx is poor since the lesion remains inactive for a long.