T-lymphoblastic leukemia. Peripheral blood smear containing leukemic cells (Wright's stain, ×200) (A). Bone marrow aspirate smear showing leukemic cells that are small-to-medium sized, with a high nuclear-to-cytoplasmic ratio (Wright-Giemsa stain, ×200 (B) and ×1,000 (C)). Biopsy section showing hypercellularity with heavy infiltration of immature cells (H&E, ×100) (D). Simultaneous translocation of both TCR Loci (14q11) with rare partner loci (Xq22 and 12p13) in a case of T-lymphoblastic leukemia. Kang DH, Kim SH, Jun JW, Lee YW, Shin HB, Ahn JY, Hong DS, Lee YK, Jeon BR - Annals of laboratory medicine (2012). Not altered. CC.
Acute Leukemia Acute leukemia is the neoplastic proliferation of blast cells. The abnormal blood cells in acute leukemia are immature blood cells called blasts. Acute leukemia is defined as the accumulation of greater than 20% blasts in the bone marrow….
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