Representative magnetic resonance imaging (MRI) abnormalities (arrows) in NMOSD patients with autoimmune diseases. (A) Bilateral thalamic lesions; (B) Bilateral hypothalamus lesions; (C) Basal ganglia lesion; (D) Hypothalamus and periventricular lesions; (E) Aqueduct of the midbrain lesion; (F) Cervico-medullary lesion; (G) Pons lesion; (H) Cerebellum lesion; (I) Longitudinally extensive transverse myelitis (LETM) lesions. Neuromyelitis optica spectrum disorders without and with autoimmune diseases: Zhang B, Zhong Y, Wang Y, Dai Y, Qiu W, Zhang L, Li H, Lu Z - BMC neurology (2014). Not altered. CC.
Autoimmune Disorders Characterized by tissue damage caused by the immune system. In the US, the prevalence of autoimmune disorders is 1%. Autoimmune disorders involve losing tolerance for oneself. Although self-reactive lymphocytes are regularly produced, they undergo apoptosis (negative selection) in…
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