Ischemic Heart Disease

Ischemic Heart Disease Pathology Study Guide

Ischemic Heart Disease Ischemic Heart Disease Pathology Video Ischemic heart disease is a group of syndromes associated with myocardial ischemia. Ischemic heart disease is the major cause of death in the United States of America (USA). Ischemic heart disease is…
Multiple Myeloma

Plasma Cell Disorder Pathology Study Guide

Plasma Cell Disorders (Dyscrasias) Plasma Cell Disorders Pathology Video Plasma cell disorders are also known as plasma cell dyscrasias. Examples of plasma cell disorders include: Multiple myeloma (MM) Monoclonal gammopathy of undetermined significance (MGUS) Waldenstrom macroglobulinemia (WM) Multiple Myeloma Multiple…
Pulmonary Langerhans Cell Histiocytosis

Langerhans Cell Histiocytosis Pathology Study Guide

Langerhans Cell Histiocytosis Langerhans Cell Histiocytosis Pathology Video The skin is the primary location of Langerhans cells, which are specialized dendritic cells. Langerhans cells are derived from bone marrow monocytes.  Langerhans cells present antigen to naive T cells. A neoplastic…
Polyarteritis Nodosa

Vascular Pathology Study Guide

Vascular Pathology Video Vascular pathology refers to disorders that effect the vascular system. Key take home points to know about vascular pathology includes the following: Vasculitis Pathology Study Guide Hypertension Pathology Study Guide Arteriosclerosis, Aortic Dissection and Aneurysm Pathology Study…
Splenic Marginal Zone Lymphoma

Lymphoma Pathology Study Guide

Lymphadenopathy (LAD) Lymphoma Pathology Video Large lymph nodes are referred to as lymphadenopathy (LAD). Typically, lymph nodes that are draining an area of acute infection show painful lymphadenopathy (acute lymphadenitis). Causes of lymphadenopathy include: Benign lymph node hyperplasia Reactive lymph…
Increased Reticulin in Marrow in Myeloproliferative Disorder

Myeloproliferative Disorders Pathology Study Guide

Myeloproliferative Disorders Myeloproliferative Disorders Pathology Video Myeloproliferative disorders are neoplastic proliferation of myeloid cells. Myeloproliferative disorders typically occur in late adulthood (average age is 55-years-old). Myeloproliferative disorders are associated with: Leukocytosis (high white blood cell count) Hypercellular bone marrow In…
Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Chronic Leukemia Pathology Study Guide

Chronic Leukemia Chronic Leukemia Pathology Video Chronic leukemia involves leukemia of mature blood cells. Chronic leukemia is typically insidious in onset and visible in elderly adults. Examples of chronic leukemias include: Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) Hairy cell leukemia…
T-cell Acute Lymphoblastic Leukemia/Lymphoma (T-ALL)

Acute Leukemia Pathology Study Guide

Acute Leukemia Acute Leukemia Pathology Video Acute leukemia is the neoplastic proliferation of blast cells. The abnormal blood cells in acute leukemia are immature blood cells called blasts.  Acute leukemia is defined as the accumulation of greater than 20% blasts…
Normocytic Anemia

Normocytic Anemia Pathology Study Guide

Normocytic Anemia Normocytic Anemia Pathology Video Normocytic anemia is anemia with normal sized red blood cells (MCV = 80 - 100 micrometers3). Normocytic anemia is typically due: Raised peripheral destruction of red blood cells (RBCs) Underproduction of red blood cells…
Macrocytic Anemia

Macrocytic Anemia Pathology Study Guide

Macrocytic Anemia Macrocytic Anemia Pathology Video Macrocytic anemia is anemia with MCV > 100 micrometer3. Macrocytic anemia is usually caused by folate or vitamin B12 deficiency (megaloblastic anemia). Folate and vitamin B12 are required for synthesis of DNA precursors. Folate…