Central Nervous System Developmental Anomalies Central Nervous System Developmental Pathology Video Neural Tube Defects The incomplete closure of the neural tube causes neural tube defects (NTDs). Early in gestation, the neural plate invaginates to create the neural tube, which follows…
Central Nervous System Developmental Pathology Study Guide

Central nervous system white matter lesions. 45-year-old male. T2 Brain MR image showed widespread, punctuated and confluent white matter lesions from periventricular to subcortical spaces. These lesions are associated with severe axonal injury (gliosis).Fibrosis: a key feature of Fabry disease with potential therapeutic implications.
Weidemann F, Sanchez-Niño MD, Politei J, Oliveira JP, Wanner C, Warnock DG, Ortiz A - Orphanet journal of rare diseases (2013). Not Altered. CC.