How do Cells Respond to Stress?

HOW DO CELLS RESPOND TO STRESS
(A) Endogenous hGle1 is localized to SGs. HeLa cells were either left untreated or exposed to heat shock at 45°C for 60 min. Cells were processed for immunofluorescence using anti-hGle1 and G3BP antibodies. (B) hGle1 is not a component of P bodies. Immunofluorescence of hGle1 and P-body marker Dcp1a in HeLa cells treated with either heat shock or left untreated. Cytoplasmic hGle1A regulates stress granules by modulation of translation: Molecular biology of the cell (2015). Not altered. CC.

Cellular responses to stress include:  

Hypertrophy: Increase in size.

Hyperplasia: Increase in number.

  • Physiologic Hyperplasia 
  • Pathologic Hyperplasia 

Atrophy: Degeneration due to lack of use.  

Metaplasia: The development of a specific type of cell as a replacement for another type of cell that would normally be present.