(a) Peripheral blood (Wright-Giemsa, 100x) showed leukopenia with neutropenia and circulating pseudo-Pelger-Huet cells with bilobed hyposegmented nuclei. Peripheral blood also showed mild normocytic anemia and thrombocytopenia. (b) Bone marrow aspirate (Wright-Giemsa, 100x) showing a mild increase in blasts (7% of cellularity) with a high nuclear to cytoplasmic ratio, vesicular chromatin, and prominent nucleoli with variable granularity. Translocation (6;15)(q12;q15): A Novel Mutation in a Patient with Therapy-Related Myelodysplastic Syndrome: Ali SF, Sonu RJ, Dwyre DM, Jonas BA, Rashidi HH - Case reports in hematology (2015). Not altered. CC.
Leukopenia and Leukocytosis Hematopoiesis is a stepwise maturation of CD34+ hematopoietic stem cells. From the bone marrow, hematopoietic cells develop and are released into the blood. A white blood cell (WBC) count of 5,000 – 10,000 WBCs per microliter is…
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