Complex multigenic disorders include:  Normal karyotypeStructural abnormalities of chromosomesChromosomal disordersTrisomiesTrisome 21Trisomy 18Trisomy 13Trisomy 22 DiseaseClinical FeaturesDown syndrome (trisomy 21)Intellectual disability, prominent epicanthal folds, single palmar crease, flat facies, incurved 5th finger, gap between 1st 2 toes, duodenal atresia, Hirschsprung disease,…