Traumatic Brain Injuries Pathology Study Guide

Intracranial Pressure
Lateral plain radiograph of the skull shows subdural Intracranial pressure monitoring sensor (arrow), placed at the posterior temporal bone margin, after the initial decompressive craniectomy.Significance of intracranial pressure monitoring after early decompressive craniectomy in patients with severe traumatic brain injury. Kim DR, Yang SH, Sung JH, Lee SW, Son BC - Journal of Korean Neurosurgical Society (2014). Not Altered. CC.

Traumatic Brain Injuries Pathology Video

Epidural Hematoma

An epidural hematoma develops when blood accumulates between the skull and dura mater.

Epidural hematomas are usually the result of skull fracture and rupture of a major vessel of the brain.

Neurologic symptoms like lucid intervals may come initially.

Radiology of epidural hematomas classically show a lens-shaped lesion representing the dura separated from the skull by hemorrhage.

Complications of epidural hematomas include herniation, seizure, and death.

  • Epidural Hematoma
    Epidural Hematoma. Non-contrast CT scan of a traumatic acute hematoma in the right fronto-temporal area. Jpogi - Not altered. CC BY-SA 3.0

Subdural Hematoma

An accumulation of blood on the surface of the brain is known as a subdural hematoma.

Subdural hematomas develop after trauma because the bridging veins between the dura and arachnoid rupture.

Radiology of subdural hematomas reveal a lesion with a crescent shape.

Subdural hematomas may present with neurologic symptoms that progress with the severity of the hematoma.

Age-related cerebral atrophy, which stretches the veins, contributes to an increased incidence rate of subdural hematomas in the elderly.

Herniation is a potentially lethal complication of a subdural hematoma.

  • Subdural Hematoma
    Subdural Hematoma. A subdural hematoma demonstrated by CT Lucien Monfils - Not altered. CC BY-SA 3.0

Herniation

The displacement of brain tissue as a result of a force or higher intracranial pressure is known as herniation.

The most frequent type of intracranial herniation is a subfalcine herniation.

In subfalcine herniation the brain tissue protrudes through the falx cerebri.

Uncal herniation is another type of herniation, in which the temporal lobe uncus is displaced under the tentorium cerebelli.

In an uncal herniation, compression of cranial nerve III, the oculomotor nerve, causes the ipsilateral eye to move “down and out” and the pupil to dilate.

Other potential complications of herniation include:

  • Cardiopulmonary arrest occurs when the brain stem is compressed
  • Infarction of the occipital lobe or the opposite homonymous hemianopia are caused by compression of the posterior cerebral artery
  • Infarction occurs when the anterior cerebral artery is compressed
  • Seizure(s)
  • Death
  • Herniation
    Herniation. MRI showing damage due to herniation. This patient was left with residual disabilities including those involving movement and speech. Rehman T, Ali R, Tawil I, Yonas H. Not altered. CC BY 2.0