Adenosarcomas of endometrial stroma are are a group of mixed mesenchymal tumors most commonly arising from the endometrium, benign glandular epithelium and low-grade sarcoma.

What is the Pathology of Endometrial Stroma Adenosarcomas?

The pathology of endometrial stroma adenosarcomas is:

-Etiology: The cause of endometrial stroma adenosarcomas is presence of benign epithelial elements combined with a malignant mesenchymal component.

-Genes involved: ZC3H7B–BCOR, JAZF1-SUZ12 gene.

-Pathogenesis: The sequence of events that lead to endometrial stroma adenosarcomas are malignant proliferation.

-Morphology: The morphology associated with endometrial stroma adenosarcomas shows broad leaflike architecture.

-Histology: The histology associated with endometrial stroma adenosarcomas shows malignant cells.

How does Endometrial Stroma Adenosarcomas Present?

Patients with endometrial stroma adenosarcomas typically females of any age. The symptoms, features, and clinical findings associated with endometrial stroma adenosarcomas include: Abnormal vaginal bleeding, menorrhagia, menstrual disorder. 

How is Endometrial Stroma Adenosarcomas Diagnosed?

Endometrial stroma adenosarcomas is diagnosed by: dilation and curettage, hysterectomy to remove uterus.  

How is Endometrial Stroma Adenosarcomas Treated?

Endometrial stroma adenosarcomas is treated by: total hysterectomy and bilateral ovariectomy

What is the Prognosis of Endometrial Stroma Adenosarcomas?

The prognosis of endometrial stroma adenosarcomas is fair. The Five-year survival rates are 58.18%