The slit-lamp photograph of the dilated eye of the proband. (A) Slit-lamp photograph of the lens of the proband showing the nuclear cataract. All the affected individuals in the family have the same manifestations of nuclear cataract. (B) Photograph taken of the proband indicating a normal cornea and iris: a nuclear cataract was present. A novel COL4A1 gene mutation results in autosomal dominant non-syndromic congenital cataract in a Chinese family. Xia XY, Li N, Cao X, Wu QY, Li TF, Zhang C, Li WW, Cui YX, Li XJ, Xue CY - BMC medical genetics (2014). Not Altered. CC.