(A) The figure shows a C. trachomatis infected inclusion under acute conditions at 20 hrs PI. (B) The figure shows a C. trachomatis infected inclusion within a HEp-2 cell in the presence of 50 U/ml IFN-γ at 20 hrs PI. TEM was conducted as described in Methods. The scale bar represents 1 μM. Chlamydia trachomatis responds to heat shock, penicillin induced persistence, and IFN-gamma persistence by altering levels of the extracytoplasmic stress response protease HtrA: Huston WM, Theodoropoulos C, Mathews SA, Timms P - BMC microbiology (2008). Not altered. CC.