Diffuse alveolar haemorrhage. (A) The lung biopsy specimen has variable fresh blood in the parenchyma, typically associated with fibrin, reactive type 2 cells and haemosiderin-filled alveolar macrophages (B). This reaction pattern may be associated with immunologically mediated injury. (A,B) H&E stain; (A) 40× original magnification; (B) 400× original magnification. My approach to interstitial lung disease using clinical, radiological and histopathological patterns. Leslie KO - Journal of clinical pathology (2009). Not Altered. CC.
Diffuse pulmonary hemorrhage syndromes are a collection of symptoms that occur due to the extensive bleeding of the lungs and they may include hemoptysis, hypoxemia with respiratory failure a drop in the hematocrit levels and the presence of diffuse pulmonary infiltrates.
Examples of diffuse pulmonary hemorrhage syndromes include:
- Goodpasture syndrome
- Idiopathic pulmonary hemosiderosis
- Polyangiitis with granulomatosis
