Morphological changes of local advanced gastric cancer before and after preoperative chemotherapy. (A) Gross gastric carcinoma (endoscopy view) before chemotherapy. (B) Obviously shrunk gastric carcinoma (endoscopy view) after chemotherapy in the same patient. (C) Tumor tissue surrounded by inflammatory tissue (arrow) after chemotherapy. H & E staining, original magnification ×40. (D) Gastric cancer cells showed obvious nucleus necrosis after chemotherapy. H & E staining, original magnification ×100. Comparison between better and poorly differentiated locally advanced gastric cancer in preoperative chemotherapy: a retrospective, comparative study at a single tertiary care institute. Sun LB, Zhao GJ, Ding DY, Song B, Hou RZ, Li YC - World journal of surgical oncology (2014). Not Altered. CC.