What are Mucinous Tumors of the Ovary?

Mucinous Tumors of the Ovary
(a) Mucinous cystic neoplasm of ovary with mural nodule (b) A well-circumscribed SLMN alongwith borderline mucinous tumor (H and E, ×100) (c) A cellular well-demarcated nodular area of SLMN (H and E, ×100) (d) Complex atypical cribriform glands of borderline mucinous neoplasm (H and E, ×400). Sarcoma-like mural nodule in a borderline mucinous tumor of the ovary: A rare entity. Ghosh P, Saha K, Bhowmik S - Journal of mid-life health (2014). Not Altered. CC.

Mucinous Tumors of the Ovary are epithelial ovarian tumors that arise from the transformed cells of the coelomic epithelium that look like the cells of the endocervical epithelium endocervical or müllerian type. 

What is the Pathology of Mucinous Ovarian Tumors?

The pathology of mucinous ovarian tumors is:

-Etiology: The cause of mucinous ovarian tumors is genetic mutations.

-Genes involved: KRAS, BRAF, TP53 and CDKN2A genes/

-Pathogenesis: The sequence of events that lead to mucinous ovarian tumors is malignant proliferation.

-Morphology: The morphology associated with mucinous ovarian tumors shows endocervical-type differentiation.

-Histology: The histology associated with mucinous ovarian tumors shows stromal invasion, intestinal type glands, signet ring cells.

How does Mucinous Ovarian Tumors Present?

Patients with mucinous ovarian tumors typically are females in 20s and 40s years of age. The symptoms, features, and clinical findings associated with mucinous ovarian tumors include: large ovarian mass felt in belly, bloating, fatigue, pain.

How is Mucinous Ovarian Tumors Diagnosed?

Mucinous ovarian tumors is diagnosed by: blood tests for CA125, trans-vaginal ultrasound, CT scan, MRI.  

How is Mucinous Ovarian Tumors Treated?

Mucinous ovarian tumors is treated by surgery, chemotherapy, platinum-based chemotherapy drugs.

What is the Prognosis of Mucinous Ovarian Tumors?

The prognosis of mucinous ovarian tumors is good. Most women are cured and have no further problems. There is a small risk of the tumor returning.