Comparison of expression patterns of fibrillin-2 in healthy, granular type I and lattice type I stromal dystrophy corneal buttons, and the colocalization of matrilin-2 and fibrillin-2 in corneal epithelium. Healthy samples showed mild immunolocalization in superficial and basal epithelial layers (A). In addition to the strong epithelial immunopositivity of fibrillin-2 in granular dystrophy, marked labeling was observed in stromal granules (B). In lattice corneal dystrophy, continuous cytoplasmic staining was found in the base of the basal columnar cells (C). Scale bar 100 μm.Fibrillin-2, tenascin-C, matrilin-2, and matrilin-4 are strongly expressed in the epithelium of human granular and lattice type I corneal dystrophies. Szalai E, Felszeghy S, Hegyi Z, Módis L, Berta A, Kaarniranta K - Molecular vision (2012). Not Altered. CC.