This is mediated by the antibodies and occurs after days of the transplant. In this rejection, immunoglobulin G antibodies are produced by the activation of the B cells against the transplanted organ or tissue.
What are the Chronic Antibody-Mediated Rejections?
Chronic Antibody Mediated Rejection. Immunohistochemical staining for C4d shows diffuse linear and strong circumferential staining in the peritubular capillaries, consistent with acute antibody-mediated rejection (C4d IHC ×100). Not Altered. CC.
Late Renal Allograft Rupture Associated with Cessation of Immunosuppression following Graft Failure.
Askandarani S, Aloudah N, Al Enazi H, Alsaad KO, Altamimi
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What are Acute Antibody-Mediated Rejections?