A: An unusual dysgenetic gonad showing distinct areas of ovarian-type stroma (O) and testicular (T) tissue, but no ovarian follicles or germ cells. B: Dysgenetic testis showing disorganized testicular tissue (T) surrounded by atypical ovarian-type stroma (O). C: Streak gonad lacking germ cells. D: Placental-like alkaline phosphatase immunostaining, seen as brown-staining (P), suggestive of delayed maturation or intratubular germ cell neoplasia unclassified.Clinical and gonadal features and early surgical management of 45,X/46,XY and 45,X/47,XYY chromosomal mosaicism presenting with genital anomalies.
Farrugia MK, Sebire NJ, Achermann JC, Eisawi A, Duffy PG, Mushtaq I - Journal of pediatric urology (2012). Not Altered. CC.
Tumors of sex cord-gonadal stroma are an assorted group of malignant or benign neoplasms, subclassified based on their presumed histogenesis and differentiation.
Tumors of sex cord-gonadal stroma include:
- Leydig cell tumors
- Sertoli cell tumors