What is a Disruption?

Disruption
(a). Group C - Heart (Control) (H&E 4 × 10) - Mild mononuclear infiltrate. (b). Group CH - Heart (H&E 10 × 10) - Myocyte disruption (1st from left arrow), cholesterol clefts, (IInd from left arrow), and mononuclear infiltration. (IIIrd from left arrow), (c). Group Se - Kidney (H&E 10×10) - Disruption of muscle fibres (upper arrow) and mononuclear infiltration (lower arrow). (d). Group CH+Se - Heart (H&E 10×10) - mononuclear infiltration (1st from left arrow) and Myocyte disruption (IInd from left arrow). Histopathological changes due to the effect of selenium in experimental cockerels. Latheef SA, Radhika K, Subramanyam G - The Indian journal of medical research (2014). Not Altered. CC.

A disruption is a non-progressive, congenital morphologic anomaly due to the breakdown of a body structure that had a normal developmental potential.

Examples of disruptions include:

  • Facial clefts
  • Missing digits
  • Missing limbs