What is a Primary Ovarian Carcinoid Tumors within a Cystic Teratoma?

Primary Ovarian Carcinoid Tumors within a cystic teratoma
a Gross appearance of the left ovary: A multicystic mass containing viscous sebaceous material and hair is visible. b, c Uniform cells are arranged in cords and trabeculae beneath the respiratory epithelium. d, e Tumor cells showing positivity for CD56 and synaptophysin. f The Ki-67 proliferative index in the carcinoid tumor is 1 %. A carcinoid tumor arising from a mature cystic teratoma in a 25-year-old patient: a case study. Kim JY - World journal of surgical oncology (2016). Not Altered. CC.

Primary ovarian carcinoid tumors within a cystic teratoma are relatively rare tumors that resemble well-differentiated neuroendocrine tumors of the gastrointestinal tract. 

What is the Pathology of Primary Ovarian Carcinoid Tumors within a Cystic Teratoma?

The pathology of primary ovarian carcinoid tumors within a cystic teratoma is:

-Etiology: The cause of primary ovarian carcinoid tumors within a cystic teratoma is unknown.

-Genes involved: CDX2.

-Pathogenesis: The sequence of events that lead to primary ovarian carcinoid tumors within a cystic teratoma.

-Morphology: The morphology associated with primary ovarian carcinoid tumors within a cystic teratoma shows multicystic masses containing viscous sebaceous material and hairs.

-Histology: The histology associated with primary ovarian carcinoid tumors within a cystic teratoma shows cysts with different tissue types.

How does Primary Ovarian Carcinoid Tumors within a Cystic Teratoma Present?

Patients with primary ovarian carcinoid tumors within a cystic teratoma typically females at intra- or postmenopause or >40 years age. The symptoms, features, and clinical findings associated with primary ovarian carcinoid tumors within a cystic teratoma include: pelvic mass, abdominal distension and pelvic pain, abnormal uterine bleeding.

How is Primary Ovarian Carcinoid Tumors within a Cystic Teratoma Diagnosed?

Primary ovarian carcinoid tumors within a cystic teratoma is diagnosed by CT scan, MRI, ultrasonography, blood tests for CA125 levels, physical examination, and biopsy.

How is Primary Ovarian Carcinoid Tumors within a Cystic Teratoma Treated?

Primary ovarian carcinoid tumors within a cystic teratoma is treated by: hysterectomy with bilateral salpingo-oophorectomy, and fertility-sparing surgery.

What is the Prognosis of Primary Ovarian Carcinoid Tumors within a Cystic Teratoma?

The prognosis of primary ovarian carcinoid tumors within a cystic teratoma is good. Generally most of the patients remain clear of tumour recurrence or metastasis during follow-up.