What is A Thalasemia?

Thalasemia
Thalasemia. Photo by Hush Naidoo Jade Photography.

A thalasemia is a syndromes group of genetic anemias of varying clinical severity.

What is the Pathology of A Thalasemia?

The pathology of α thalasemia is:

-Etiology: The cause of α thalasemia is gene mutation.

-Genes involved: α-globin genes

-Pathogenesis: The sequence of events that lead to α thalassemia are as the results from variety of molecular lesions result, but the most commonly deletion of α-globin.

-Morphology: The morphology associated with α thalasemia shows abnormal rashes.

-Histology: The histology associated with α thalasemia shows abnormal red blood cells.

How does A Thalasemia Present? 

Patients with α thalasemia typically have no sex prevarence present at age range of infancy. The symptoms, features, and clinical findings associated with α thalasemia include, anamia, severe pallor, and hydrops fetalis.

How is A Thalasemia Diagnosed? 

A thalasemia is diagnosed through laboratory evaluation such as hemoglobin electrophoresis, and genetic testing.

How is A Thalasemia Treated? 

A thalasemia is treated through managing symptoms if any, iron and folic acid supplementation.

What is the Prognosis of A Thalasemia?

The prognosis of α thalasemia is good for silent carriers, poor for hydrops fetalis.